
Cell Line Development
What Are Cell Lines?
Cell lines are self-replicating, living cultures derived from animal tissues. The La Crosse Fish Health Center specializes in developing novel lines from fish and amphibians to isolate aquatic viruses.
Why Cell Lines Matter
Cell cultures are a foundational tool in aquatic animal health, serving as the gold standard for isolating and detecting viral pathogens in fish and amphibians. When diagnostic tissue samples are inoculated onto susceptible cell lines, target viruses replicate within the cultured cells. This interaction produces characteristic cytopathic effects (CPE), visible cellular damage that can be observed under a microscope, allowing our laboratory to identify active viral infections and safeguard aquatic populations
Advancing Diagnostic Capabilities
Our lab actively expands its repository by establishing novel cell lines. These efforts support:
