U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock () or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Colorful containers with cell lines in them in a fridge.

Cell Line Development

Updated September 28, 2026

What Are Cell Lines?

Cell lines are self-replicating, living cultures derived from animal tissues. The La Crosse Fish Health Center specializes in developing novel lines from fish and amphibians to isolate aquatic viruses.

Why Cell Lines Matter

Cell cultures are a foundational tool in aquatic animal health, serving as the gold standard for isolating and detecting viral pathogens in fish and amphibians. When diagnostic tissue samples are inoculated onto susceptible cell lines, target viruses replicate within the cultured cells. This interaction produces characteristic cytopathic effects (CPE), visible cellular damage that can be observed under a microscope, allowing our laboratory to identify active viral infections and safeguard aquatic populations

Advancing Diagnostic Capabilities

Our lab actively expands its repository by establishing novel cell lines. These efforts support:

Colorful containers with cell lines in them in a fridge.

Contact Us

The La Crosse Fish Health Center collaborates with academic institutions, state agencies, and research facilities worldwide. To explore research partnerships, submit diagnostic cases, or collaborate on taxonomic descriptions, contact us below.

Explore more: